HomeGamesSega GenesisPlay Duke Nukem 3D Sega Genesis Play Duke Nukem 3D Nominate for Retro Game of the Day! Play Duke Nukem 3D Online Play this Sega Genesis game in your web browser, here on GamePhD! Use Chrome/Firefox if Internet Explorer doesn’t load the game. Final Thoughts If you had fun playing, consider rating this game on a scale of 1-5 stars! Overall Score 3.9 Your Rating Visitors Rating 0 votes 0